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( C ) Relative mRNA expression of -catenin and TCF7L2 in Control and Emodin groups under different glucose conditions, detected by real-time PCR

These formulations may ease barriers related to manufacturing, supply chains, and access

Common side effects may include temporary skin irritation, mild redness, or sensitivity at application sites, particularly during initial treatment phases

The duration of the infusion may vary depending on dosage and tolerability

In alcohol tests in which Ex4, liraglutide, or dulaglutide was injected repeatedly, there was no development of tolerance toward the GLP-1R agonists tested (Suchankova et al., 2015